Skin assessment
Skin consultation and quality assessment by the dermatologist.
PDRN Skin Regeneration
Polynucleotide (PDRN) Injection for Skin Elasticity & Radiance
A highly purified, clinical-grade Polymerized Polynucleotides (PN-HPT) skin booster that stimulates fibroblasts to improve hydration, elasticity, and skin quality.
Polynucleotide (PDRN) injections use purified salmon DNA fragments to activate fibroblast proliferation and skin repair pathways. At Skin Clinic by Dr. Eram Razzaq, sessions are planned for facial rejuvenation, under-eye improvement, neck and décolleté, and hand skin quality — with a typical course of 3 to 4 sessions spaced 2 to 4 weeks apart.
3-4
Sessions in a course
PDRN
Biological skin repair
Glow
Radiance & elasticity
Treatment Overview
What are polynucleotide (PDRN) injections?
Polynucleotide injections deliver purified salmon-derived DNA fragments (polydeoxyribonucleotide) into the skin to stimulate fibroblast activity, collagen synthesis, and tissue repair. Unlike fillers that add volume, PDRN improves the biological quality of skin — targeting hydration, elasticity, fine lines, and overall skin health. Treatment areas include the face, under-eyes, neck, and hands.
Not sure if this treatment is right for your skin?
Book a consultation so Dr. Eram can examine your concern, review history, and guide you safely.
Key benefits
Stimulates fibroblast activity to improve skin elasticity and firmness.
Provides deep biological hydration that topical moisturizers cannot replicate.
Improves skin texture, tone, and reduces the appearance of fine lines.
Can visibly improve tired or dehydrated under-eye skin quality.
Suitable for face, neck, décolleté, and hands in a single course.
Suitability
Who should consider this treatment?
Suitability is confirmed after skin examination, medical history, lifestyle review, and realistic expectation setting.
Good candidate signs
May be suitable for
- Patients with dull, dehydrated, or aging-looking skin.
- Those with early elasticity loss, fine lines, or loss of skin plumpness.
- Under-eye area showing hollowing, crepiness, or dull discoloration.
- Patients wanting biological skin regeneration without filler volume.
- Those following aesthetic procedures who want enhanced skin recovery.
Doctor review needed
Needs caution or may avoid
- Active skin infection or inflammation at the injection site.
- Known allergy to salmon or fish-derived compounds (PDRN is salmon DNA-derived).
- Pregnant or breastfeeding patients without medical clearance.
- Patients expecting filler-level volume replacement from a skin-quality treatment.
Why choose Dr. Eram for this procedure?
Dr. Eram plans the PDRN course based on skin age, laxity, target area, and hydration deficit.
Micro-injection technique distributes PDRN evenly for natural-looking improvement.
Treatment stimulates the skin repair process, not just surface hydration.
Clear expectations about progressive, biologically driven improvement are discussed upfront.
Procedure Journey
What to expect during your session
01
Skin consultation and quality assessment by the dermatologist.
02
Cleansing and topical numbing of the treatment area if required.
03
Micro-injections of PDRN placed into the dermis across the target zone.
04
Post-treatment soothing care and session schedule guidance.
Results & Recovery
Expected timeline
Immediately: Small injection bumps visible at treatment points, typically settling within hours.
First week: Early improvement in hydration and skin freshness is often felt.
4 to 6 weeks: Texture, firmness, and glow progressively improve through the course.
After 3 to 4 sessions: Full result becomes visible and may last 6 to 12 months with maintenance.
Aftercare
How to protect your results
- Avoid makeup, excessive heat, saunas, or steam for 24 hours after treatment.
- Do not massage or press injection sites unless instructed by the doctor.
- Use SPF 30+ sunscreen and gentle skincare in the days following treatment.
- Return for follow-up sessions on the planned schedule for best results.
Treatment Process
Your polynucleotide injection journey in clear steps
A clear appointment pathway helps you understand assessment, procedure planning, recovery guidance, and follow-up before booking.
Safe planning
Cleansing and topical numbing of the treatment area if required.
Procedure session
Micro-injections of PDRN placed into the dermis across the target zone.
Review & recovery
Post-treatment soothing care and session schedule guidance.
Patient Reviews
Patient feedback for polynucleotide injection
Patient feedback focused on consultation quality, comfort, aftercare guidance, and realistic treatment planning.
Ayesha Khan
“Very smooth consultation. Dr. Eram explained why polynucleotide injection was suitable and what I should expect after the session.”
Sana Malik
“I was nervous before visiting, but the doctor checked my concern carefully, explained the treatment steps, and gave simple aftercare instructions. The visit felt organized, clean, and professional.”
Hina Riaz
“Clear guidance and no rushed treatment.”
Usman Raza
“The team guided me about session planning, recovery time, and follow-up. I appreciated the realistic expectations instead of over-promising instant results.”
Maryam Ahmed
“My concern was discussed in detail, and the clinic team made the whole process easy to understand from consultation to aftercare.”
FAQs
Common questions before booking
These answers are general guidance. Your actual plan depends on examination, skin type, medical history, and treatment suitability.
What are polynucleotide (PDRN) injections?
PDRN injections deliver purified salmon DNA fragments into the dermis to stimulate fibroblast activity, skin repair, hydration, and elasticity.
How are they different from fillers?
Fillers add structural volume. PDRN focuses on biological skin quality improvement — hydration, texture, elasticity, and repair.
How many sessions are needed?
A typical course is 3 to 4 sessions spaced 2 to 4 weeks apart, followed by maintenance every 6 to 12 months.
Can it treat the under-eye area?
Yes. PDRN can improve the quality, texture, and hydration of the under-eye area, though it does not replace volume for deep hollows.
When will I see results?
Most patients notice early hydration improvement after one session, with fuller results building progressively through the course.
Is it painful?
Most patients feel mild stinging. Topical numbing is applied to sensitive areas such as the under-eye zone.
Can it combine with fillers or Botox?
Yes. PDRN complements other injectable treatments and is often planned alongside fillers and Botox for a complete rejuvenation approach.
Who should avoid PDRN?
Patients with allergy to salmon-derived compounds, active skin infection, or those who are pregnant should avoid this treatment.
Is there visible downtime?
Minimal. Small injection marks and mild redness typically resolve within a few hours to a day.
Do I need a consultation first?
Yes. Skin type, concern, and treatment area are assessed to confirm suitability and plan the correct course.
Book Appointment
Ready to discuss polynucleotide injection?
Share your concern and the clinic team will guide you about appointment availability, suitability review, and the next step with Dr. Eram Razzaq.
Doctor-led consultation
Suitability-first planning
WhatsApp follow-up support